Abstract Background Neuroinflammation has an important role in the pathophysiology of migraine. which is a complex neuro-glio-vascular disorder. The main aim of this review is to highlight findings of cortical spreading depolarization (CSD)-induced neuroinflammatory signaling in brain parenchyma from the inflammasome perspective. In addition. https://www.voyageassistance.com/product-category/gspot/