Abstract Introduction This study aimed to investigate the long-term prognostic effects of different alteplase doses on patients with acute ischemic stroke (AIS). Methods In this cohort study. we enrolled 501 patients with AIS treated with intravenous thrombolysis with alteplase. with the primary endpoint event of recurrence of ischemic stroke and the secondary endpoint event of death. https://wholesfoodsboxs.shop/product-category/mustards/