The germinal center (GC) reaction is a key feature of adaptive humoral immunity. GCs represent the site where mature B cells refine their B-cell receptor (BCR) and are selected based on the newly acquired affinity for the antigen. In the GC. B cells undergo multiple cycles of proliferation. https://www.spidertattooz.com/Essie-Tea-Crumpets-0-5-oz-325-p15557/